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41 While coolness has been identified by young people as one of the reasons why some of their peers smoke, 42 research undertaken in Western Australia suggests that this has shifted over time, with those who smoke increasingly regarded as losers or trying too hard to be cool

For example, CBD is an inhibitor of the CYP3A4 enzyme, as are tetracycline, erythromycin, ciprofloxacin, and clarithromycin

There has been an explosive rise in the use of flavored tobacco among adolescents

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