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The most common side effects, as reported in Mounjaro clinical trials, include: Nausea Often most pronounced during the first few weeks of treatment or after dose increases Diarrhea Can range from mild to moderate and may come and go Vomiting Particularly common when eating large meals or high-fat foods Constipation Some users experience the opposite of diarrhea Abdominal pain Cramping or discomfort in the stomach area Decreased appetite While this aids weight loss, it can sometimes feel uncomfortable Stomach problems are among the most common side effects of Mounjaro, primarily causing gastrointestinal symptoms such as nausea, vomiting, diarrhea, and constipation

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Head rubbing was again the dominant behavior, making up about 85% of the response time

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