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Regular, heavy smokers will need to start on a 2% or 20mg/ml e-liquid to effectively curb cravings, and while the exact nicotine content in the vapour will vary depending on the size of the inhale, it's good to imagine that about 7 puffs on a low powered vape of 2% nicotine strength is equal to about 1 cigarettes worth of nicotine

Third, it is crucially important to carefully formulate the claims, labeling and communication materials associated with a cMRTP to ensure that the intended messages and warnings are accurate and not misleading [85], and well understood

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