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They had no clue why, but they soon found out that native people smoked the burning leaves, and when they brought these leaves back to Europe, it became a sensation

A broad review of 44 studies found that tobacco-free nicotine alternatives can support smoking cessation at around 41% , while also showing that using both cigarettes and alternative tobacco products can raise the risk of returning to cigarettes by 8.5% , according to the review hosted on PubMed Central

Durham: Carolina Academic Press, 2003

Economic substitutes which lack the qualities justifying the excise tax or feature them in a dramatically attenuated form (e.g., non-sugary beverages, vapor products, plastic alternatives) should not be included in excise tax bases