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Tobacco smoke is composed of over 4000 types of constituents, including nicotine, tar, carbon monoxide, polycyclic aromatic hydrocarbons, and heavy metals

Lastly, in a study of 206 young adults who use pod-based devices, median urinary cotinine (the major metabolite of nicotine) was 244.8 ng/ml (higher than reported for adolescent cigarette smokers [68]) [39]

Inflammation may be caused by: Severe coughing A chest injury Physical activity, particularly involving lifting Autoimmune disease or infection What is Tietze Syndrome

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