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34 Functional polymorphisms in the genes coding for these enzymes allow for the identification of fast metabolizers, who have more rapid nicotine clearance and show greater cigarette intake and more intensive smoking topography profiles relative to normal or slow metabolizers

Effects of smoking on heart rate at rest and during exercise, and on heart rate recovery, in young adults

Because those short-term effects come with devastating trade-offs like addiction, heart damage, neurological deterioration, and death