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Some devices, such as pod systems, are designed to be used with high nicotine e-liquids

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[1] Saliva testing for nicotine Saliva tests can detect nicotine for approximately 14 days post-use/exposure

'This paper does however highlight that e-cigarettes are not risk-free, and so we need additional studies to uncover their potential longer-term impacts on human health.' Commenting on the findings, George Laking, director of the Centre for Cancer Research, University of Auckland, said they should be viewed with caution, adding that the development of cancer 'is a multi-step process'

Regulations include restricting sales of e-cigarettes to customers age 18 and older, reporting detailed ingredient lists, providing tobacco health documentation, posting warning statements on packaging and advertisements that state potential risks, among other rules