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Description

Pena de la Vega L, Lieske JC, Milliner D, Gonyea J, Kelly DG

A well-designed linker ensures the therapeutic agent remains stable in circulation and is released selectively within cancer cells, minimizing harm to healthy tissues

Hansen M, Chandra A, Mitic LL, Onken B, Driscoll M, Kenyon C

Tong et al., 2011

4-Hydroxynonenal 4-Hydroxynonenal (4HNE) is a lipoperoxidation-derived aldehyde that can damage proteins and DNA through the generation of covalent adducts and is implicated in the control of cell signaling 13,14