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Archived from the original on May 8, 2019

The AORs and p-values were calculated using multiple Firths penalized likelihood logistic regression analyses with adjustment for age, physical activity, alcohol intake, body mass index, estimated glomerular filtration rate, diabetes, hypertension, and dyslipidemia

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The exploratory correlation analysis between the GMVs of ROIs and smoking history showed a negative correlation between years of smoking and volume of the right medial frontal gyrus ( r = 0.491, p = 0.02)

Key takeaways Nicotine addiction can rival addiction to heroin and other illicit substances, which means quitting smoking may take more than mental willpower alone