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Company CEO Larry Firestone said the renewal builds on FDA recognition that reducing nicotine directly can alter smoking behavior and improve public health outcomes, adding that VLN products align with the FDAs proposed low-nicotine standard issued in January 2025

These considerations show that current classification systems can underestimate the relevance of cigarette butts

The new study extends this to assess the effects of commonly used flavoring chemicals, as well as e-liquids without nicotine, directly on immune cells namely, a type of white blood cell called monocytes

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A similar argument could be made about the use of a filter itself since current scientific evidence does not support its value in improving population health [12, 18]