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As the main component of tobacco, it is associated with stimulation of the central nervous system and is linked to cardiovascular diseases and various cancers

From the bustling streets of Tokyo to the quaint cafes of Paris, pack cigarettes have left their mark on diverse cultures and communities, reflecting the global appeal of this timeless smoking accessory

Table 1 demonstrates the distribution of age, sex, race-ethnicity, poverty-income ratio, insurance status, BMI, serum cotinine, and epilepsy in those with and without tobacco smoke exposure

However, Pfizer had no further role in the study design, collection, analysis and interpretation of the data, writing of the report, or in decision to submit the paper for publication.Trial registration:ClinicalTrials.gov Identifier: NCT02894957 Date of Acceptance: July 14, 2022 | Published Online Date: July 22, 2022 Abbreviations: chronic obstructive pulmonary disease, COPD