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7j) where both ionocytes and PNECs differentiate from POU2F3 + tuft-like cells, and whereby blockade of FOXI1 -dependent ionocyte differentiation increases abundance of both tuft-like cells and PNECs

The activation of these sites sends signals to the brain that promote neurotransmitter emission and the stimulation of the sympathetic nervous system, leading to pleasurable effects coupled with stimulating effects such as higher heart rate and increases alertness

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