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Steven S, Oelze M, Hausding M, Roohani S, Kashani F, Kroller-Schon S, Helmstadter J, Jansen T, Baum C, Iglarz M, Schulz E, Munzel T, Daiber A (2018) The endothelin receptor antagonist macitentan improves isosorbide-5-mononitrate (ISMN) and isosorbide dinitrate (ISDN) induced endothelial dysfunction, oxidative stress, and vascular inflammation

However, the researchers note that a former smoker can still have increased health risks three decades after giving up tobacco

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