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Its not clear: which type of cannabinoid either natural or synthetic might be most effective what kind of doses might be needed which types of cancer might respond best to cannabinoids how to avoid the psychoactive effects of THC how best to get cannabinoids, which dont dissolve easily in water, into cancer cells whether cannabinoids will help to boost or counteract the effects of chemotherapy These questions must be answered for cannabinoids to be used as safe and effective treatments for cancer patients