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C-fibres that innervate the airways originate in both the nodose and jugular vagal ganglia, and are found predominantly within the airway epithelium

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Food and Drug Administration (FDA) for treating alcohol use disorder (AUD) and opioid use disorder (OUD), naltrexone has been explored for other co-occurring conditions with mixed results. For individuals with co-occurring AUD and post-traumatic stress disorder (PTSD), the study Pharmacotherapy for Co-Occurring Alcohol Use Disorder and Post-Traumatic Stress Disorder by Terril L Verplaetse, et al