DOTA-PEG6-propargyl Size:5mg NRX-2663 acts as molecular glue

NRX-2663 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome

82 SMILES ClCCOCCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

NRX-252114 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome

British Journal of Pharmacology n/a

Product Name Phthalimidinoglutarimide-5'-C3-O-PEG2-OH Synonyms CAS Number n/a Related CAS Molecular Formula C20H26N2O6 Molecular Weight 390

DOTA-PEG6-propargyl Size:5mg NRX-2663 acts as molecular glueDOTA bifucational chelator containing an alkyne group, a PEG linker, and the macrocyclic chelator DOTA ( 1,4,7,10 tetraazacyclododecane 1,4,7,10 tetraacetic acid). It can be used in many different diagnostic and therapeutic applications, such as MRI contrast agents, PET and SPECT imaging agents, and radiotherapeutic agents. Product Name DOTA PEG6 propargyl Synonyms CAS Number n a Related CAS Molecular Formula C31H55N5O13 Molecular Weight 705. 803