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Back in the day, some Gibson guitars that fell short of the companys rigorous quality control were demoted as seconds and subsequently stamped with a 2 (although most guitarists wouldnt notice any significant disadvantages)

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Nicotine exposure in adolescence has been associated with mood disorders, and problems with memory, attention, impulse control, and cognition later in life.[88] Pesticides and Other Chemicals Many child tobacco workers interviewed for this report said they handled or applied pesticides, fertilizers, or other chemical agents to tobacco farms in their communities, often without wearing suitable protective equipment