Lenalidomide-5'-CO-PEG4-C2-amine HCl acid 493 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)ON2C(=O)CCC2=O)CCN(CC(O)=O)CC1 Purity (HPLC)

493 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)ON2C(=O)CCC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

394 SMILES OCCCCCCC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

It induces degradation of SALL4 (ZF2)

48 SMILES Cl

It can also be reversibly coupled to aldehydes and ketones to form a Schiff base - which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3)

Lenalidomide-5'-CO-PEG4-C2-amine HCl acid 493 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)ON2C(=O)CCC2=O)CCN(CC(O)=O)CC1 Purity (HPLC)Degrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Lenalidomide 5' CO PEG4 C2 amine HCl Synonyms CAS Number n a Related CAS 2727154 04 1 (free base) Molecular Formula C24H35ClN4O8 Molecular Weight 543. 01 SMILES Cl. NCCOCCOCCOCCOCCC(=O)NC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O