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Nonclinical Toxicology 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility A 2-year carcinogenicity study was conducted with tirzepatide in male and female rats at doses of 0.15, 0.50, and 1.5 mg/kg (0.1-, 0.4-, and 1-fold the MRHD of 15 mg once weekly based on AUC) administered by subcutaneous injection twice weekly

Can J Gastroenterol Hepatol 2018:17

Indeed, women that lose minimal weight from their lower abdomen, hips, and legs after bariatric surgery should be examined for the presence of lipedema

doi:10.1007/s10787-009-0027-7