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Therefore, integrating patient-specific vasculature is crucial for advancing immune-competent aOoC systems and ensuring reliable disease modelling, particularly in immune-mediated and inflammatory disorders

its activity could be stimulated by the GSH intracellular levels

Further, studies show that about 20 ~ 30% of patients with metastatic melanoma initially respond to immune checkpoint blockade treatment but eventually develop resistance and relapse after therapy (173, 174)

Discussion APR-246 can restore the wild-type conformation of mutant p53 protein, therefore inducing apoptosis and inhibition of tumor growth in mice

Multiple linear regression analysis was performed to investigate the influencing factors for cognitive improvement in FES patients, by limiting the effects of confounding factors, such as age, education and baseline BMI