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NAD+, short for nicotinamide adenine dinucleotide, is a coenzyme found in all living cells

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Vitamin B6: Though some research suggests vitamin B6 could help alleviate some of the emotional symptoms of PMDD, the small amount in this supplement is most likely added to help the body better metabolize the supplemental 5-HTP into serotonin.64 65 Lions mane: While research is still emerging, lions mane may help support mood and reduce inflammation.66 The amount included here is relatively modest compared to doses used in clinical studies, so it likely plays more of a supporting role in the formula

Mateu L, Izquierdo L, Franco A et al: Pain relief after triamcinolone infiltration in patients with bladder pain syndrome with hunner's ulcers