TMP3-TMR trametiglue Auxin regulates SCFTIR1-dependent degradation of
TMP3-TMR trametiglue Auxin regulates SCFTIR1-dependent degradation ofThe TMP tag is based on the tight binding between trimethoprim (TMP), a synthetic antibiotic, and Escherichia coli dihydrofolate reductase (eDHFR), a small enzyme with a high affinity for TMP. By fusing eDHFR to a protein of interest and introducing TMP linked to a probesuch as a fluorescent dye, biotin, or other functional groupresearchers can selectively label and study proteins in their native cellular environment. TMP3 TMR is a third generation
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