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Biochemical and preclinical investigations suggest that AOD 9604 affects pathways involved in cellular energy regulation, including cyclic AMP signaling and downstream kinase activation

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Galactose modified prodrugs Duocarmycin Senescent cells are characterized by high levels of (SA--Galactosidase) implying that generation of prodrugs combining a cytotoxic compound linked to a cleavable galactose part should be preferentially processed by those cells