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This is particularly beneficial within a balanced diet and regular exercise program

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& Chung, J

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This comprehensive search utilized databases such as PubMed, Scopus, and Web of Science, with keywords including ME/CFS, Gut-Brain Axis, Gut Health, Intestinal Dysbiosis, Microbiome Dysbiosis, Pathophysiology, and Therapeutic Approaches. Where possible, insights from clinical trials and observational studies were included to enrich the findings

Tricyclic antidepressants, such as cyclobenzaprine are dosed at 520 mg or nortriptyline, initiated at a dose of 10 mg at bedtime, while SNRIs like duloxetine and venlafaxine are started at 30 mg and 37.5 mg daily, respectively, titrated to a maximum of 50% of that used in non-cirrhotic population