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These vitamins are essential for maintaining the myelin sheath that protects nerve fibers

doi: 10.1016/j.jneuroim.2009.04.004 75 SmithPASchmidCZurbrueggSJivkovMDoelemeyerATheilDet al

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In synaptic mitochondria, the major role in control over oxidative phosphorylation is attributed to complex I that at 25% inhibition, energy metabolism is disturbed and ATP synthesis is drastically affected