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Several limitations of this study warrant consideration

Cells (2021) 10(9):121

Time on ART also impacted on the AM cellular response to stress via inactivation of reactive oxygen species (ROS) and protein turnover via the unfolded protein response (UPR) ( Figure 4B )

At the cellular level, neuron death in PD is more systemic than previously assumed: non-invasive imaging recently demonstrated that the nerve supply to the heart degenerates in PD subjects