Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE AHPC CA-Tetrazine is a HaloTag ligand

CA-Tetrazine is a HaloTag ligand containg a methayltetrazine group for click chemistry applications

638 Purity (HPLC) >= 95% Solubility DMSO

and limited aquous solubility

369 SMILES BrCCOCCOCCOCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

in particular

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE AHPC CA-Tetrazine is a HaloTag ligandSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to