Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg Product Name DOTA-tris(t-Bu)ester-PEG3-C2-propanamido-maleimide Synonyms CAS

Product Name DOTA-tris(t-Bu)ester-PEG3-C2-propanamido-maleimide Synonyms CAS Number n/a Related CAS Molecular Formula C43H75N7O13 Molecular Weight 898

Fagherazzi

Product Name CA-Ac Synonyms Acetyl-Halo

544 SMILES [N-]=[N+]=NCCOCCOCCOCCOCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

and relatively pH-insensitive fluorescence

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg Product Name DOTA-tris(t-Bu)ester-PEG3-C2-propanamido-maleimide Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan,