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Glycolysis is a catabolic pathway that breaks down glucose to yield ATP and pyruvate

Mutations in parkin ( PRKN ) or phosphate and tensin homolog-induced kinase 1 ( PINK1 ) prevent cells from responding to mitochondrial damage by altering the balance of fusion to fission and disrupting mitophagy, which leads to familial forms of PD [97, 98]

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PMID 9989458

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