DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-PNP sir Product Name DOTA-C6-amine Synonyms CAS

Product Name DOTA-C6-amine Synonyms CAS Number n/a Related CAS Molecular Formula C22H42N6O7 Molecular Weight 502

This compound is a highly potent and efficacious degrader

Product Name BC-BCN Synonyms CLIP-BCN CAS Number Related CAS Molecular Formula C23H26N4O3 Molecular Weight 406

Indisulam promotes the recruitment of RBM39 (RNA binding motif protein 39) to the CUL4-DCAF15 E3 ubiquitin ligase

It features a disulfide bond

DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-PNP sir Product Name DOTA-C6-amine Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine