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Smedfors G, Olson L, Karlsson T

The phagocytized non-photosynthetic bacteria (symbionts) over eons evolved into mitochondria while the engulfed photosynthesizing bacteria became chloroplasts (known as the well-established endosymbiotic theory) of the early eukaryotes and during this process the melatonin-synthesizing capacity of the bacteria-derived organelles, both chloroplasts and mitochondria, was retained ( Figure 2 )

Then, membrane pellets were resuspended in a Dounce homogenizer in lysis buffer

Increased brain lactate during depressive episodes and reversal effects by lithium monotherapy in drug-naive bipolar disorder: a 3-T 1H-MRS study

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