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10.1038/nrn2755 Nat

The possibility of herb-drug interactions, in which specific nutraceuticals may change the pharmacokinetics or pharmacodynamics of prescription medications, is a serious safety concern

In addition, selenium levels have been found to be decreased in patients with chronic kidney disease (CKD)

Nanocarriers can also be used for combined application of DOX with genetic tools or anti-cancer compounds (85)

Achieving consistent control over these critical parameters across large-volume industrial reactors remains a key challenge that must be overcome for widespread commercial adoption