Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) peg6 Product Name DOTA-tris(t-Bu)ester-C5-propanamido-maleimide Synonyms CAS

Product Name DOTA-tris(t-Bu)ester-C5-propanamido-maleimide Synonyms CAS Number n/a Related CAS Molecular Formula C40H69N7O10 Molecular Weight 808

It also has higher quantum yield and extinction coefficient

It has the spectral properties identical to those of other ROX conjugates

can be hydrolyzed by intracellular esterases to release the fluorescent fluorescein core

Abdul-Hadi

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) peg6 Product Name DOTA-tris(t-Bu)ester-C5-propanamido-maleimide Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from established