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In conclusion, TAA is a carcinogen and a hepatotoxicant and is known as a nephrotoxicant, which induced structural kidney damage including severe tubular epithelial cell death associated with inflammatory cell infiltration, sclerosis and necrosis of the glomeruli, and fibrosis 9,11,13,14,15

Overexpression of cGAS significantly reduces the number of micronuclei in an autophagy-dependent manner independent of its role in cGAS-STING signaling

10.13457/j.cnki.jncm.2021.17.003 191 YangJ.ZhangW.LinB.MaoS.LiuG.TanK.et al (2024)

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Cagrilintide + Tirzepatide Clinical Evidence Context Direct stack evidence No published human trial has tested cagrilintide + tirzepatide together