Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-MMAE chloride Product Name Phthalimidinoglutarimide-propargyl-PEG3-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG3-OH

Product Name Phthalimidinoglutarimide-propargyl-PEG3-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG3-OH CAS Number n/a Related CAS Molecular Formula C22H26N2O7 Molecular Weight 430

65 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCC#C)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name CA-DOTA-tris(t-Bu) Synonyms HaloTag DOTA-tris(t-Bu) Ligand

Product Name Lenalidomide-CO-C2-acid Synonyms Lenalidomide-4'-CO-C2-acid CAS Number 1488107-60-3 Related CAS Molecular Formula C17H17N3O6 Molecular Weight 359

CA-PEG4-Lissamine Rhodamine B is a HaloTag Ligand containg Lissamine Rhodamine B dye

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-MMAE chloride Product Name Phthalimidinoglutarimide-propargyl-PEG3-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG3-OHSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly