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In summary, the action of valproate in neural systems is complex, with one aspect including downregulation of PKC signaling, which overlaps with symptom amelioration of manic states in animal models, suggesting that modulation of PKC overactivity is a mechanism that is favored by valproate

In this review, we summarize the updated achievements regarding the structure and biological function of ACSL4 and report how ACSL4-mediated ferroptosis and disordered lipid metabolism contribute to human diseases

In addition, the authors showed that under an oxidative stress condition (H 2 O 2 -treated wild-type plants), CML10 mRNA levels and AsA levels increase rapidly and significantly, but the expression level of the PMM gene does not change

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