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Deletion of the key catalytic enzyme methylthioadenosine phosphorylase (MTAP) gene is associated with the sensitivity of GSK3368715, 331 and a current phase II clinical study of GSK3368715 in breast cancer has been enrolled (NCT04676516) (Table 1)

Next, we identified two yet undefined progenitor-like cell clusters (expressing pcna and cdk1 ), which did not show any obvious cell-type marker, a B cell cluster (for example, expressing swap70a , cd74b and cd79a ), a natural killer (NK) cell cluster and two smaller hematopoietic stem cell (HSC) clusters

Current Pharmaceutical Design, 17 (16), 16121632

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