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CTRP13 mitigates endothelial cell ferroptosis via the AMPK/KLF4 pathway: implications for atherosclerosis protection

Glutathione is synthesized in a two-step process, in which the first and rate-limiting enzyme -glutamylcysteine synthetase (ECS or GSH1) converts glutamate and cysteine to EC, then glutathione synthetase (GSH2) forms glutathione by the ligation of an additional glycine to the intermediate 42,43 (Fig

Table 2 IBD treatments with synthetic antioxidants

These methods enable deeper exploration of the molecular foundations of depression [377]

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