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It is, therefore, possible that redox thresholds in B cells are subset-specific, and that these thresholds mediate homeostatic functions that could account for the differing properties of MZB and FoB

As an additional test of the specificity of the effect, we find that the decrease in glutamate brought by acivicin could be rescued by administration of pyroglutamate (5-oxoproline), a downstream metabolite in the glutathione pathway that is a precursor of glutamate ( SI Appendix , Fig

Furthermore, they can also be more easily operated than MS in regions with unreliable power supply

then studied the effects of mitochondrial ROS on T cell function and expansion

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