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Contraindications for investigational use should be discussed with a healthcare provider and may include Wilsons disease (a copper accumulation disorder), pregnancy (no data), or known allergy to copper/peptides

We show that treatment of slices with 1 mM CPZ induces acute demyelination that resolves at 1-week post-treatment, but cannot be sustained by chronic administration, nor the addition of rapamycin, as achieved in vivo

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