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In the current study, CPZ consumption elicited behavioral and motor anomalies as established by tail suspension test and inverted screen grip strength test in both CPZ-DE and CPZ-RE groups compared to normal controls

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Hence, elucidating the underlying pathophysiological mechanisms contributing to the emergence of cardiovascular diseases holds immense importance in terms of preventing, detecting at an early stage, and providing accurate treatment for CVD

Sodium l-lactate and sodium d-lactate (Sigma Aldrich) were dissolved in Neurobasal medium (Thermo Fisher Scientific) and added before hypoxia at different concentrations (51020 mM of l-lactate and 10 mM of d-lactate)

Secondary antibodies used were horseradish peroxidase-linked anti-rabbit (CST, ##7074, 1:5000 dilution), horseradish peroxidase-linked anti-mouse (CST, #7076, 1:5000 dilution), DyLight-800 4 PEG-linked anti-rabbit (CST, #5151, 1:5000 dilution), and DyLight 680-linked anti-mouse (CST, #5470, 1:5000 dilution)