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However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007

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Trial interventions and procedures Surgery and implantable system A baseline visit assessed operability based on a complete workup (clinical examination, electrocardiogram, biological workup and chest X-ray) and brain magnetic resonance imaging

(Documents that pyridoxine is FDA Pregnancy Category A with increased requirements in pregnancy and is commonly used to treat morning sickness