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Safety and precautions: Because pure bacteriostatic water is hypotonic, it should not be injected alone intravenously (doing so can cause red cell hemolysis)

Assessments were performed immediately after treatment and after 12 weeks

Well, in Brasil, they are not given saline solution, if BBC is to be trusted

If you want a plain-language rundown of symptoms and patterns, the Crohns overview is a good place to start

Patients with known or unrecognized neuromuscular disorders or neuromuscular junction disorders may be at increased risk of clinically significant effects, including generalized muscle weakness, diplopia, ptosis, dysphonia, dysarthria, severe dysphagia, and respiratory compromise from therapeutic doses of BOTOX (see Warnings and Precautions )