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Also, using shorter-acting drugs to avoid prolonged drug metabolism time in older patients is recommended (reduce exposure of brain to agents that may perturb mitochondria)

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Intracellularly, heme is catabolized by heme oxygenase releasing the heme-iron that enters known iron pools with regulatory consequences and potentially as iron levels rise iron export

[DOI] [PubMed] [Google Scholar] 21.Baker M.A., Cerniglia G.J., Zaman A