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The kynurenine pathway is responsible for at least 90% of tryptophan catabolism and is predominantly active in the epithelial, immune and mesenchymal cells of the gastrointestinal tract [59]

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Counts per million of 3-tRFs and i-tRFs lacking our motif (green) and carrying it (purple), from ribosome associated RNA-seq (left) or bulk short RNA-seq (right) in resting cells, or in cells right after or two hours post depolarization (2 h pDP)