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View Study [5]"Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise" Hameed M, Orrell RW, Cobbold M, Goldspink G, Harridge SD, 2003 Finding: This human study revealed a critical age-related problem: after resistance exercise, young people showed a significant increase in MGF, but elderly subjects did not

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Overall, IEP-Lip, which targets the ectodomain of IR, could induce an immune response, but in contrast, the PEG-ITP-Lip/ITP-Lip formulations did not present a similar risk, which may be attributable to the specific modification of ITP that reduces its exposure in serum

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