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while it revealed unchanged CAT expression in simple steatosis, a considerable reduction in fatty as well as non-fatty MASH liver samples was shown (Li et al

doi: 10.2217/nmt-2020-0033 241 SamaR

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After 60 days of treatment, improvement was sustained in those receiving 60 mg per day, with a nearly 48% increase in tear production compared with baseline, but had diminished slightly in those receiving 30 mg per day

Overall, these results demonstrated that genistein reduces inflammation, ferroptosis, and the function of SGECs by downregulating ACSL4