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doi:10.1111/jth.12986 Betts JG, Young KA, Wise JA, et al

Safety Precautions: LEMONBOTTLE is not suitable for individuals with specific medical conditions, Liver & Kidney disease or disorders, Diabetes, Thyroid disorders, permanent use of anticoagulants, skin disease and disorders in the target area such as psoriasis, eczema, scabiesetc, Scar tissue (not to treat tissue area until 6 months post healing) current infection or illness, excessive weight loss

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Moreover, there exists evidence linking elevated Hcy levels to an increased risk of MetS (Sreckovic et al., 2017)