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Duration of treatment depends on the underlying cause: Lifelong therapy is required for pernicious anaemia or irreversible malabsorption (e.g., after gastrectomy) For dietary deficiency without malabsorption, treatment may be reviewed once deficiency is corrected and neurological symptoms have resolved Oral B12 supplementation is generally not recommended for patients with neurological symptoms, particularly when pernicious anaemia is the cause

**Not all patients are a candidate for every treatment

As a vital body component, vitamin B12 plays a role in DNA synthesis, red blood cell production, and neurological function

Now I see that still waters run deep

Both work as a research protocol