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The Ab Pcob crystals were obtained from 8% w/v PEG 20000, 8% v/v PEG 550 MME, 0.1 M sodium acetate, pH 5.5, 0.2 M potassium thiocyanate

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All patients met the 2010 American College of Rheumatology RA classification criteria and were participants of an established RA inception cohort